Mazindol Lose, Generic Name: mazindol (MA zin doll) Brand Names: MZ1 What is mazindol? Mazindol is a sympathomimetic amine, which is similar to an amphetamine. It is also known as an “anorectic” or an “anorexigenic” drug. Mazindol stimulates the central nervous system (nerves and brain), which increases your heart rate and blood pressure and decreases your appetite. Mazindol is used as a short-term supplement to diet and exercise in the treatment of obesity. Mazindol may also be used for purposes other than those listed in this medication guide.