Description
Clinical data
Routes of
administration Smoked, Oral
Legal status
AU: S9 (Prohibited)
CA: Schedule II
DE: Anlage II (Authorized trade only, not prescriptible)
US: Schedule I
Identifiers
IUPAC name[show]
CAS Number
209414-07-3
PubChem CID
10382701
ChemSpider
8558143 Yes
ChEMBL
CHEMBL561013 Yes
ECHA InfoCard 100.163.574
Chemical and physical data
Formula C24H23NO
Molar mass 341.45 g/mol
Solubility in water hydrophobic, n/a mg/mL (20 °C)
InChI[show]
Yes (what is this?) (verify)
JWH018 is a full agonist of both the CB1 and CB2 cannabinoid receptors,
with a reported binding affinity of 9.00 ± 5.00 nM at CB1 and 2.94 ± 2.65 nM at CB2.
[3] JWH-018 has an EC50 of 102 nM for human CB1 receptors, and 133 nM for human CB2 receptors.
[12] JWH-018 produces bradycardia and hypothermia in rats at doses of 0.3–3 mg/kg,
suggesting potent cannabinoid-like activity. Buy jwh-018 online and get discreet packaging